optimum body maintenance means that about 10 billion of human cells will die on a normal day just to counter the numbers of new cells that arise through mitosis.
during development apoptosis helps to sculpture the body shape the organs and carve out fingers and toes. both the nervous system and the immune system arise through overproduction of cells followed by the death of those that fail to establish functional synaptic connections or productive antigen specificitiesrespectively. apoptosis is necessary to purge the body of pathogen-invaded cells but is also needed to eliminate activated or auto-aggressive immune cells.
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