Hi Scott,
Are you using ASIO drivers?
If not you can try this setting which normally works on most soundcards:
1) Switch off DSP.
2) go to menu: media/ASIO(via port audio)
3) set Delay(msec): 6ms
4) set Block size : 256
5) On the i/o devices pull-down menu select your "ASIO:<soundcard name>"